Type Papers Patents Conferences
Page 1 2 3 4 5 6 7 8 all-in-one
  1. Tae Yoon Kim, Jin Ho Park, Ha Eun Shim, Dae Seong Choi, Dong-Eun Lee, Ji-Joon Song, Hak-Sung Kim; "Prolonged half-life of small-sized therapeutic protein using serum albumin-specific protein binder," Journal of Controlled Release. 2019 December, 315: 31-39 file
  2. Sumin Son, Jinho Park, Hyodeok Seo, Hyun Tae Lee, Yong-Seok Heo, and Hak-Sung Kim; "A small-sized protein binder specific for human PD-1 effectively suppresses the tumor growth in tumor mouse model," Journal of Drug Targeting. 2019 September, 1-9 file
  3. Tae-Geun Yu, Hak-Sung Kim*. and Yoonjoo Choi*; "B-SIDER: Computational Algorithm for the Design of Complementary β-sheet Sequences," Journal of Chemical Information and Modeling. 2019 September, 59(10): 4504-4511 file
  4. Yiseul Ryu, Jung Ae Kang, Dasom Kim, Song-Rae Kim, Seungmin Kim, Seong Ji Park, Seung-Hae Kwon, Kil-Nam Kim, Dong-Eun Lee, Joong-jae Lee, and Hak-Sung Kim; "Programed assembly of nucleoprotein nanoparticles using DNA and Zinc fingers for targeted protein delivery," Small. 2018 November, 14(52): e1802618 file
  5. Henry Syukur Purwanto, Mi-Sook Kang, Lenny Ferrera, Sang-Soo Han, Jin-Young Lee, Hak-Sung Kim, Jin-Ho Lee; "Rational engineering of the shikimate and related pathways in Corynebacterium glutamicum for 4-hydroxybenzoate production," Journal of Biotechnology. 2018 September; 282: 92-100 file
  6. Woosung Heu*, Jung Min Choi*, Hyun-Ho Kyeong, Yoonjoo Choi, Hee Yeon Kim, and Hak-Sung Kim; "Repeat module-based rational design of a photoswitchable protein for light-driven control of biological processes," Angew. Chem. Int. Ed., 2018 August, 57(34):10859-10863 file
  7. Tae Yoon Kim*, Hyo-Deok Seo*, Joong-jae Lee, Jung Ae Kang, Woo Sik Kim, Hye-Min Kim, Ha-Yeon Song, Ji Min Park, Dong-Eun Lee, Hak-Sung Kim (*equal contribution); "A dimeric form of a small-sized protein binder exhibits enhanced anti-tumor activity through prolonged blood circulation," Journal of Controlled Release. 2018 June; 279: 282-291 file
  8. Jong-won Kim, Joong-jae Lee, Joon Sig Choi, Hak-Sung Kim; "Electrostatically assembled dendrimer complex with a high-affinity protein binder for targeted gene delivery," International Journal of Pharmaceutics. 2018 April; 544(1): 39-45 file
  9. Jeong-Hyun Ryou*, Yoo-kyoung Sohn*, Dong-Gun Kim, Hyun-Ho kyeong, Hak-Sung Kim (*equal contribution); "Engineering and cytosolic delivery of a native regulatory protein and its variants for modulation of ERK2 signaling pathway," Biotechnology and Bioengineering. 2018 Jan; 115(4): 839-849 file
  10. Sajid Mushtaq, Jong Kook Rho, Jung Ae Kang, Joong-Jae Lee, Jung Young Kim, You Ree Nam, Seong-Jae Yun, Gyeong Hee Lee, Sang Hyun Park, Dong-Eun Lee, Hak-Sung Kim; "Radiolabeling and preliminary biodistribution study of 99mTc-labeled antibody-mimetic scaffold protein repebody for initial clearance properties," Bioorg Med Chem Lett. 2017 Nov 15;27(22):5060-5064 file
  11. Hee-Yeon Kim*, Jung Ae Kang*, Jeong-Hyun Ryou, Gyeong Hee Lee, Dae Seong Choi, Dong Eun Lee, and Hak-Sung Kim (*equal contribution); "Intracellular Protein Delivery System Using a Target-Specific Repebody and Translocation Domain of Bacterial Exotoxin," ACS Chem. Biol., 2017, 12 (11), pp 2891-2897 file
  12. Hyun-Ho Kyeong*, Yoonjoo Choi*, Hak-Sung Kim (*equal contribution); "GradDock: rapid simulation and tailored ranking functions for peptide-MHC Class I docking," Bioinformatics. 2018 Feb 1 file
  13. Ayoung Pyo, Misun Yun, Hyeon-Sik Kim, Tae-Yoon Kim, Joong-jae Lee, Jung Young Kim, Sunwoo Lee, Seong Young Kwon, Hee-Seung Bom, Hak-Sung Kim, Dong-Yeon Kim and Jung-Joon Min; "64Cu-Labeled Repebody Molecules for Imaging of Epidermal Growth Factor Receptor Expressing Tumors," J Nucl Med, 2017 September 15; 59(2): 340-346 file
  14. Misun Yun*, Dong-Yeon Kim*, Joong-jae Lee*, Hyeon-Sik Kim, Hyung-Seok Kim, Ayoung Pyo, Yiseul Ryu, Tae-Yoon Kim, Jin Hai Zheng, Su Woong Yoo, Hoon Hyun, Gyungseok Oh, Jaeho Jeong, Myeongju Moon, Jung-Hyun Min, Seong Young Kwon, Jung Young Kim, Euiheon Chung, Yeongjin Hong, Wansik Lee, Hak-Sung Kim, Jung-Joon Min (*equal contribution); "A High-Affinity Repebody for Molecular Imaging of EGFR-Expressing Malignant Tumors," Theranostics 2017; 7(10):2620-2633 file
  15. Jong-won Kim, Woosung Heu, Sukyo Jeong, Hak-Sung Kim; "Genetically functionalized ferritin nanoparticles with a high-affinity protein binder for immunoassay and imaging," Anal. Chim. Acta, 2017 Octover; 988:81-88 file
  16. Joong-jae Lee*, Jung Ae Kang*, Yiseul Ryu, Sang-Soo Han, You Ree Nam, Jong Kook Rho, Dae Seong Choi, Sun-Woong Kang, Dong-Eun Lee, Hak-Sung Kim (*equal contribution); "Genetically engineered and self-assembled oncolytic protein nanoparticles for targeted cancer therapy," Biomaterials, Volume 120, 2017 March; 120: 22-31 file
  17. Soo-Jin Yeom, Dae-Hee Lee, Yu Jung Kim, Jeongmin Lee, Kil Koang Kwon, Gui Hwan Han, Haseong Kim, Hak-Sung Kim, Seung-Goo Lee; "Long-term stable and tightly controlled expression of recombinant proteins in antibiotics-free conditions," PLoS One, 2016; 11(12): e0166890 file
  18. Hyo-Deok Seo, Joong-jae Lee, Yu Jung Kim, Oliver Hantschel, Seung-Goo Lee, Hak-Sung Kim; "Alkaline phosphatase-fused repebody as a new format of immuno-reagent for an immunoassay," Anal. Chim. Acta, 2016 Epub, 2017; 950: 184-191 file
  19. Sukyo Jeong, Woosung Heu, Jong-won Kim, and Hak-Sung Kim; "Protein binders specific for immunoglobulin G with a different origin for immunoassays and multiplex imaging," Anal. Chem., 2016, 88(23), 11938-11945 file
  20. Sang-Soo Han*, Hyun-Ho Kyeong*, Jung Min Choi*, Yoo-Kyoung Sohn, Jin-Ho Lee, and Hak-Sung Kim (*equal contribution); "Engineering of the conformational dynamics of an enzyme for relieving the product inhibition," ACS Catalysis, 2016; 6(12): 8440-8445 file
  21. Da-Eun Hwang, Jung-Min Choi, Chul-Su Yang, Joong-jae Lee, Woosung Heu, Eun-Kyeong Jo, and Hak-Sung Kim (*equal contribution); "Effective suppression of C5a-induced proinflammatory response using anti-human C5a repebody," Biochemical and Biophysical Research Communications, 2016, 477(4), 1072-1077 file
  22. Da-Eun Hwang, Yong-Keol Shin, Palinda Ruvan Munashingha, So-Yeon Park,Yeon-Soo Seo, Hak-Sung Kim; "A Repeat Protein-Based DNA Polymerase Inhibitor for an Efficient and Accurate Gene Amplification by PCR," Biotechnology and Bioengineering, 2016, 113(12), 2544-2552 file
  23. Yu Jung Kim and Hak-Sung Kim; "Improved metagenome screening efficiency by random insertion of T7 promoters," Journal of Biotechnology, 2016, 230, 47-53 file
  24. Da-Eun Hwang, Jeong-Hyun Ryou, Jong Rok Oh, Jung Woo Han, Tae Kwann Park, Hak-Sung Kim; "Anti-Human VEGF Repebody Effectively Suppresses Choroidal Neovascularization and Vascular Leakage," PLoS ONE, 2016, 11(3), e0152522 file
  25. Young-Pil Kim, Hak-Sung Kim; "Nanoparticles for Use in Enzyme Assays," ChemBioChem, 2016, 17(4), 275-282 file
  26. Jeong-Hyun Ryou, Yoo-Kyoung Sohn, Da-Eun Hwang, Woo-Yong Park, Nury Kim, Won-Do Heo, Mi-Young Kim, Hak-Sung Kim; "Engineering of bacterial exotoxins for highly efficient and receptor-specific intracellular delivery of diverse cargos," Biotechnology and Bioengineering , 2016, 113(8), 1639-1646 file
  27. Hee-Yeon Kim, Joong-jae Lee, Nury Kim, Won Do Heo, Hak-Sung Kim; "Tracking protein–protein interaction and localization in living cells using a high-affinity molecular binder," Biochemical and Biophysical Research Communications , 2016, 470(4), 857-863 file
  28. Sisi Patricia Lolita Ameria, Hye Sook Jung, Hee Sook Kim, Sang Soo Han, Hak Sung Kim, Jin Ho Lee; "Characterization of a flavin-containing monooxygenase from Corynebacterium glutamicum and its application to production of indigo and indirubin," Biotechnol Lett, 2015, 37, 1637–1644 file
  29. Sang-Soo Han, Won-Ji Park, Hak-Sung Kim, and Geun-Joong Kim; "Antisense RNA-based High-Throughput Screen System for Directed Evolution of Quorum Quenching Enzymes," ACS Chem. Biol. , 2015, 10(11), 2598-2605 file
  30. Joong-jae Lee, Hyo-Jung Choi, Misun Yun, YingJin Kang, Ji-Eun Jung, Yiseul Ryu, Tae Yoon Kim, Young-je Cha, Hyun-Soo Cho, Jung-Joon Min, Chul-Woong Chung, and Hak-Sung Kim; "Enzymatic Prenylation and Oxime Ligation for the Synthesis of Stableand Homogeneous Protein–Drug Conjugates for Targeted Therapy," Angew. Chem. Int. Ed., 2015, 127(41), 12188-12192 file
  31. Jeong-Hyun Ryou, Yoo-Kyoung Sohn, Da-Eun Hwang, Hak-Sung Kim; "Shiga-like toxin-based high-efficiency and receptor-specific intracellular delivery system for a protein," Biochemical and Biophysical Research Communications, 2015, 464(4), 1282-1289 file
  32. Jin Ho Bae, Seong-Min Jo, Hak-Sung Kim; "Comprehensive detection of diverse exon 19 deletion mutations of EGFR in lung Cancer by a single probe set," Biosensors and Bioelectronics, 2015, 74, 849–855 file
  33. Jung-Min Choi*, Sang-Soo Han*, Hak-Sung Kim (*equal contribution); "Industrial applications of enzyme biocatalysis: Current status and future aspects," Biotechnology Advances, 2015, 33(7), 1443-1454 file
  34. Sang Jin Park*, Jung Min Choi*, Hyun-Ho Kyeong*, Song-Gun Kim and Hak-Sung Kim (*equal contribution); "Rational Design of a β-Glycosidase with High Regiospecificity for Triterpenoid Tailoring," ChemBioChem, 2015, 16(5), 854-860 file
  35. Hyegeun Min*, Seong-Min Jo*, and Hak-Sung Kim (*equal contribution); "Efficient Capture and Simple Quantification of Circulating Tumor Cells Using Quantum Dots and Magnetic Beads," Small, 2015, 11(21), 2536-2542 file file
  36. Seong-Min Jo, Joong-jae Lee, Woosung Heu, and Hak-Sung Kim; "Nanotentacle-Structured Magnetic Particles for Efficient Capture of Circulating Tumor Cells," Small, 2015, 11(16), 1975-1982 file file
  37. Hyun-Ho Kyeong*, Jin-Hyun Kim* and Hak-Sung Kim (*equal contribution); "Design of N-acyl homoserine lactonase with high substrate specificity by a rational approach," Applied Microbiology and Biotechnology, 2014, 99(11), 4735-4742 file
  38. Yiseul Ryu*, Zongwen Jin*, Joong-jae Lee, Seung-hyun Noh, Tae-Hyun Shin, Seong-Min Jo, Joonsung Choi, HyunWook Park, Jinwoo Cheon, and Hak-Sung Kim (*equal contribution); "Size-Controlled Construction of Magnetic Nanoparticle Clusters Using DNA-Binding Zinc Finger Protein," Angew. Chem. Int. Ed., 2015, 54(3), 923-926 file file
  39. Jeong-Hyun Ryou, Keunwan Park, Joong-jae Lee, Dongsup Kim, Hak-Sung Kim; "Soluble expression of human glycoprotein Iba in Escherichia coli through replacement of the N-terminal capping domain," Protein Expression and Purification, 2014, 101(9), 21-27 file
  40. Seong-Min Jo, Seung-hyun Noh, Zongwen Jin, Yongjun Lim, Jinwoo Cheon, Hak-Sung Kim; "Simple and efficient capture of EGFR-expressing tumor cells using magnetic nanoparticles," Sensors and Actuators B: Chemical, 2014, 201, 144-152 file
  41. Young-Su Jeong, Jung Min Choi, Hyun-Ho Kyeong, Jae-Youl Choi, Eui-Joong Kim, Hak-Sung Kim; "Rational design of organophosphorus hydrolase with high catalytic efficiency for detoxifying a V-type nerve agent," Biochemical and Biophysical Research Communications, 2014, 449(3), 263-267 file
  42. Woosung Heu, Jung-Min Choi, Joong-Jae Lee, Sukyo Jeong, and Hak-Sung Kim; "Protein Binder for Affinity Purification of Human Immunoglobulin Antibodies," Analytical Chemistry, 2014, 86(12), 6019-6025 file
  43. Yuno Lee*, Joong-jae Lee*, Songmi Kim*, Sang-Chul Lee, Jieun Han, Woosung Heu, Keunwan Park, Hyun Jung Kim, Hae-Kap Cheong, Dongsup Kim, Hak-Sung Kim, Keun Woo Lee (*equal contribution); "Dissecting the Critical Factors for Thermodynamic Stability of Modular Proteins Using Molecular Modeling Approach," PLOS ONE, 2014, 9(5), e98243 file
  44. Hyang Choi, Hyun-Ho Kyeong, Jung Min Choi, Hak-Sung Kim; "Rational design of ornithine decarboxylase with high catalytic activity for the production of putrescine," Applied Microbiology and Biotechnology, 2014, 98(17), 7483-7490 file
  45. Joong-jae Lee*, Hyun Jung Kim*, Chul-Su Yang*, Hyun-Ho Kyeong, Jung-Min Choi, Da-Eun Hwang, Jae-Min Yuk, Keunwan Park, Yu Jung Kim, Seung-Goo Lee, Dongsup Kim, Eun-Kyeong Jo, Hae-Kap Cheong, Hak-Sung Kim (*equal contribution); "A high-affinity protein binder that blocks the IL-6/STAT3 signaling pathway effectively suppresses non-small cell lung cancer," Molecular Therapy, 2014, 22(7), 1254-1265 file file
  46. Moon-Hyeong Seo, Jeongbin Park, Eunkyung Kim, Sungchul Hohng, Hak-Sung Kim; "Protein conformational dynamics dictate the binding affinity for a ligand," Nature Communications, 2014, 5, 3724 file
  47. Mi-Suk Kang*, Sang-Soo Han*, Mi-Young Kim, Bu-Youn Kim, Jong-Pil Huh, Hak-Sung Kim, Jin-Ho Lee (*equal contribution); "High-level expression in Corynebacterium glutamicum of nitrile hydratase from Rhodococcus rhodochrous for acrylamide production," Applied Microbiology and Biotechnology, 2014, 98(10), 4379-4387 file
  48. Su-Lim Choi, Eugene Rha, Sang Jun Lee, Haseong Kim, Kilkoang Kwon, Young-Su Jeong, Young Ha Rhee, Jae Jun Song, Hak-Sung Kim, and Seung-Goo Lee; "Toward a Generalized and High-throughput Enzyme Screening System Based on Artificial Genetic Circuits," ACS Synthetic Biology, 2014, 3(3), 163-171 file
  49. Jung Min Choi, Moon-Hyeong Seo, Hyun-Ho Kyeong, Eunkyung Kim, and Hak-Sung Kim; "Molecular basis for the role of glucokinase regulatory protein as the allosteric switch for glucokinase," PNAS, 2013, 110(25), 10171-10176 file
  50. So-Young Lee, Young Don Hong, Hak-Sung Kim, Sun-Ju Choi; "Synthesis and application of a novel cysteine-based DTPA-NCS for targeted radioimmunotherapy," Nuclear Medicine and Biology, 2013, 40, 424-429 file
  51. Seong-Min Jo*, Youngwook Kim*, Young-Su Jeong, Young Hee Oh, Keunchil Park, Hak-Sung Kim (*equal contribution); "Rapid detection of exon2-deleted AIMP2 mutation as a potential biomarker for lung cancer by molecular beacons," Biosensors and Bioelectronics, 2013, 46, 142-149 file
  52. Eunkyung Kim*, Sanghwa Lee*, Aram Jeon, Jung Min Choi, Hee-Seung Lee, Sungchul Hohng, Hak-Sung Kim (*equal contribution); "A single-molecule dissection of ligand binding to a protein with intrinsic dynamics," Nature Chemical Biology, 2013, 9, 313-318 file
  53. Jihyo Kim*, Moon-Hyeong Seo*, Sangsik Lee, Kyukwang Cho, Aerin Yang, Kyunghwa Woo, Hak-Sung Kim, and Hee-Sung Park (*equal contribution); "Simple and Efficient Strategy for Site-Specific Dual Labeling of Proteins for Single-Molecule Fluorescence Resonance Energy Transfer Analysis," Anal. Chem. 2013, 85(3), 1468-1474 file
  54. Jang-Hyuk Ahn, Young-Su Jeong, Tae Geol Lee, Young-Pil Kim, and Hak-Sung Kim; "Sensitive and multiplexed analysis of aflatoxins using time-of-flight secondary ion mass spectrometry," BioChip Journal, 2012, 6(1), 34-40 file
  55. Jang-Hyuk Ahn, Young-Pil Kim, and Hak-Sung Kim; "Effect of natural antioxidants on the lipid oxidation of microencapsulated seed oil," Food Control, 2012, 23(2), 528-534 file
  56. Young-Su Jeong, Su-Lim Choi, Hyun-Ho Kyeong, Jin-Hyun Kim, Eui-Joong Kim, Jae-Gu Pan, Eugene Rha, Jae Jun Song, Seung-Goo Lee and Hak-Sung Kim; "High-throughput screening system based on phenolics-responsive transcription activator for directed evolution of organophosphate-degrading enzymes," Protein Engineering Design & Selection, 2012, 25(11), 725-731 file
  57. Young-Pil Kim, Sang Jin Park, Dohoon Lee, and Hak-Sung Kim; "Electrochemical glucose biosensor by electrostatic binding of PQQ-glucose dehydrogenase onto self-assembled monolayers on gold," Journal of Applied Electrochemistry, 2012, 42(6), 383-390 file
  58. Bum Jin Oh, Moon-Hyeong Seo, and Hak-Sung Kim; "Insignificant role of the N-terminal cobalt-binding site of albumin in the assessment of acute coronary syndrome:discrepancy between the albumin cobalt-binding assay and N-terminal-targeted immunoassay," Biomarkers, 2012; 17(5): 394-401 file
  59. Sang-Chul Lee*, Keunwan Park*, Jieun Han*, Joong-jae Lee*, Hyun Jung Kim, Seungpyo Hong, Woosung Heu, Yu Jung Kim, Jae-Seok Ha, Seung-Goo Lee, Hae-Kap Cheong, Young Ho Jeon, Dong-sup Kim, and Hak-Sung Kim (*equal contribution); "Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering," PNAS, 2012, 109(9), 3299-3304 file
  60. Jieun Han*, Hyun Jung Kim*, Sang-Chul Lee, Seungpyo Hong, Keunwan Park, Young Ho Jeon, Dong-sup Kim, Hae-Kap Cheong, and Hak-Sung Kim (*equal contribution); "Structure-based rational design of a Toll-like receptor 4 (TLR4) decoy receptor with high binding affinity for a target protein," PLoS ONE, 2012, 7(2), e30929 file
  61. Yiseul Ryu, Zongwen Jin, Mun Suk Kang, and Hak-Sung Kim; "Increase in the detection sensitivity of a lateral flow assay for a cardiac marker by oriented immobilization of antibody," BioChip J. 2011, 5(3), 193-198 file
  62. Moon-Hyeong Seo*, Tae-Sun Lee*, Eunkyung Kim*, Young Lag Cho, Hee-Sung Park, Tae-Young Yoon, and Hak-Sung Kim (*equal contribution); "Efficient Single-Molecule Fluorescence Resonance Energy Transfer Analysis by Site-Specific Dual-Labeling of Protein Using an Unnatural Amino Acid," Anal. Chem. 2011, 83(23), 8849-8854 file
  63. Sunyoung Park*, Jieun Han*, Wanjung Kim, Gyun Min Lee, and Hak-Sung Kim (*equal contribution); "Rapid selection of single cells with high antibody production rates by microwell array," Journal of Biotechnology 156 (2011) 197-202 file
  64. Jang-Hyuk Ahn, Young-Pil Kim, and Hak-Sung Kim; "Effect of natural antioxidants on the lipid oxidation of microencapsulated seed oil," Food Control 23 (2012) 528-534 file
  65. Moon-Hyeong Seo, Jieun Han, Zongwen Jin, Dong-Won Lee, Hee-Sung Park, and Hak-Sung Kim; "Controlled and oriented immobilization of protein by site-specific incorporation of unnatural amino acid," Anal. Chem. 2011, 83(8), 2841-2845 file
  66. Yunxian Piao, Zongwen Jin, Dohoon Lee, Hye-Jin Lee, Hyon-Bin Na, Taeghwan Hyeon, Min-Kyu Oh, Jungbae Kim, and Hak-Sung Kim; "Sensitive and High-Fidelity Electrochemical Immunoassay using Carbon Nanotubes Coated with Enzymes and Magnetic Nanoparticles," Biosens. Bioelectron. 2011, 26, 3192-3199 file
  67. Sang-Chul Lee, Jin-Hyun Kim and Hak-Sung Kim; "Design and evolution of biocatalysts," Current Organic Chemistry, 2010, Vol14, 1894-1901 file
  68. Sunyoung Park, Wanjung Kim, Yongtae Kim, Young Dok Son, Sang-Chul Lee, Eunkyung Kim, Sung Ho Kim, Jung Hoe Kim and Hak-Sung Kim; "Array-Based Analysis of Secreted Glycoproteins for Rapid Selection of a Single Cell Producing a Glycoprotein with Desired Glycosylation," Anal. Chem. 2010, 82(13), 5830-5837 file
  69. Jin-Hyun Kim, Sang-Chul Lee, Hyun-Ho Kyeong, and Hak-Sung Kim; "A Genetic Circuit System Based on Quorum Sensing Signaling for Directed Evolution of Quorum-Quenching Enzymes," ChemBioChem, 2010, 11, 1748-1753 file file
  70. Young-Hee Oh*, Youngwook Kim*, Young-Pil Kim, Soo-Won Seo, Tetsuya Mitsudomi, Myung-Ju Ahn, Keunchil Park, and Hak-Sung Kim (*equal contribution); "Rapid detection of the epidermal growth factor receptor mutation in non-small cell lung cancer for analysis of acquired resistance using molecular beacon," The Journal of Molecular Diagnostics 2010, 12(5), 644-652 file
  71. Min-Kyu Han*, Young-Hee Oh*, Jimin Kang, Young-Pil Kim, Soowon Seo, Jhingook Kim, KeunChil Park and Hak-Sung Kim (*equal contribution); "Protein profiling in human sera for identification of potential lung cancer biomarkers using antibody microarray," Proteomics 2009, 9(24), 5544-5552 file
  72. Sung Ho Yang, Kyung-Bok Lee, Bokyung Kong, Jin-Hyun Kim, Hak-Sung Kim, Insung S. Choi; "Biomimetic Encapsulation of Individual Cells with Silica," Angew. Chem. Int. Ed. 2009, 48, 9160-9163 file
  73. Kwang-Seok Yun, Dohoon Lee, Hak-Sung Kim, Euisik Yoon; "Multifunctional microwell plate for on-chip cell and microbead-based assays," Sensors and Actuators B: Chemical, 2009. 143(1), 387-394 file
  74. Yunxian Piao, Dohoon Lee, Jinwoo Lee, Taeghwan Hyeon, Jungbae Kim, Hak-Sung Kim; "Multiplexed immunoassay using the stabilized enzymes in mesoporous silica," Biosens. Bioelectron. 2009. 25(4), 906-912 file
  75. Zongwen Jin*, Young Ki Hahn*, Eunkeu Oh, Young-Pil Kim, Je-Kyun Park, Seung Ho Moon, Jung-Tak Jang, Jinwoo Cheon, and Hak-Sung Kim (*equal contribution); "Magnetic Nanoclusters for Ultrasensitive Magnetophoretic Assays," Small 2009, 5, 2243-2246 file file
  76. Young-Pil Kim, Zongwen Jin, Eunkyung Kim, Sunyoung Park, Young-Hee Oh and Hak-Sung Kim; "Analysis of in vitro SUMOylation using bioluminescence resonance energy transfer (BRET)," Biochem. Biophys. Res. Commun. 2009, 382, 530-534 file
  77. Yunxian Piao, Dohoon Lee, Jungbae Kim, Jaeyun Kim, Taeghwan Hyeon, and Hak-Sung Kim; "High performance immunoassay using immobilized enzyme in nanoporous carbon," Analyst 2009, 134, 926-932 file file
  78. Sang-Chul Lee, YoungJung Chang, Dong-Min Shin, Jieun Han, Moon-Hyeong Seo, Hossein Fazelinia, Costas D. Maranas, Hak-Sung Kim; "Designing the substrate specificity of d-hydantoinase using a rational approach," Enzyme and Microbial Technology. 2009. 44, 170-175 file
  79. Young Ki Hahn, Jae-Byum Chang, Zongwen Jin, Hak-Sung Kim, and Je-Kyun Park; "Magnetophoretic position detection for multiplexed immunoassays using colored microspheres in a microchannel," Biosens. Bioelectron. 2009, 24, 1870-1876 file
  80. Young-Pil Kim, Sunyoung Park, Eunkeu Oh, Young-Hee Oh and Hak-Sung Kim; "On-Chip Detection of Protein Glycosylation Based on Energy Transfer between Nanoparticles," Biosens. Bioelectron. 2009. 24(5), 1189-1194 file
  81. Soon Hyouk Lee, Gyuchang Lim, Soo Yong Kim, Eun Kyung Kim, Hak Sung Kim, Sok Won Kim*; "Statistical Analysis of Fluorescence Correlation Spectroscopy of Ultra Low Concentration Molecules with a Confocal Microscope," Journal of the Optical Society of Korea. 2008. 12(3), 170-173 file
  82. Young-Pil Kim, Bong Soo Lee, Eunkyung Kim, Insung S. Choi, Dae Won Moon, Tae Geol Lee, and Hak-Sung Kim; "Activity-Based Assay of Matrix Metalloproteinase on Nonbiofouling Surfaces Using Time-of-Flight Secondary-Ion Mass Spectrometry," Anal. Chem. 2008. 80(13), 5094-5102 file
  83. Young-Pil Kim*, Young-Hee Oh*, Eunkeu Oh, Sungho Ko, Min-Kyu Han,and Hak-Sung Kim (*equal contribution); "Energy Transfer-Based Multiplexed Assay of Proteases by Using Gold Nanoparticle and Quantum Dot Conjugates on a Surface," Anal. Chem. 2008. 80(12), 4634-4641 file file
  84. Eunkyung Kim, Bong Soo Lee, Hyeon-Bong Pyo, Hyun-Woo Song, Young-Pil Kim, Insung S. Choi and Hak-Sung Kim*; "Fabrication of Nonbiofouling Surface and Its Application to Surface Plasmon Field-Enhanced Fluorescence Spectroscopy," Biochip J. 2008, 2(2), 103-110 file
  85. Young-Pil Kim, Mi-Young Hong, Hyun Kyong Shon, Won Chegal, Hyun Mo Cho, Dae Won Moon, Hak-Sung Kim*, and Tae Geol Lee*; "Protein Quantification on Dendrimer-Activated Surfaces by Using Time-of-Flight Secondary Ion Mass Spectrometry and Principal Component Regression," Appl. Surf. Sci. 2008. 255, 1110-1112 file
  86. Young-Pil Kim, Eunkeu Oh, Hyun Kyong Shon, Dae Won Moon, Tae Geol Lee*, and Hak-Sung Kim*; "Gold Nanoparticle-Enhanced Secondary Ion Mass Spectrometry And Its Bio-applications," Appl. Surf. Sci. 2008. 255, 1064-1067 file
  87. Young-Pil Kim, Young-Hee Oh, and Hak-Sung Kim; "Protein Kinase Assay on Peptide-Conjugated Gold Nanoparticles," Biosens. Bioelectron. 2008, 23, 980-986 file
  88. Jang-Hyuk Ahn, Young-Pil Kim, Yu-Mi Lee, Eun-Mi Seo, Ki-Woong Lee and Hak-Sung Kim; "Optimization of microencapsulation of seed oil by response surface methodology," Food Chem. 2008, 107, 98-105 file
  89. Jang-Hyuk Ahn, Young-Pil Kim, Eun-Mi Seo, Young-Ki Choi, and Hak-Sung Kim; "Antioxidant Effect of Natural Plant Extracts on the Microencapsulated High Oleic Sunflower Oil," J. Food Eng. 2008, 84, 327-334 file
  90. Young-Pil Kim, Young-Hee Oh, Eunkeu Oh, and Hak-Sung Kim; "Chip-based protease assay using fluorescence resonance energy transfer between quantum dots and fluorophores," Biochip J. 2007, 1(4), 228-233 file
  91. Young-Pil Kim, Kun Cho, Dohoon Lee, Yunxian Piao, Yeong Hee Ahn, Jong Shin Yoo, Taeghwan Hyun and Hak-Sung Kim; "Efficient Enrichment and Desalting of Protein Digests Using Magnetic Mesocellular Carbon Foams in Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry," Rapid Commun. Mass Spectrom. 2007, 21, 3435-3442 file
  92. Jae Seung Yang, Hye Jin Kim, Cheol-Heui Yun, Seok-Seong Kang, Jintaek Im, Hak-Sung Kim, and Seung Hyun Han; "A semi-automated vibriocidal assay for improved measurement of cholera vaccine-induced immune responses," J. Microbiol. Meth. 2007, 71, 141-146 file
  93. Young-Pil Kim, Eunkeu Oh, Young-Hee Oh, Dae Won Moon, Tae Geol Lee, and Hak-Sung Kim; "Protein Kinase Assay on Peptide-Conjugated Gold Nanoparticles by Using Secondary Ion Mass Spectrometric Imaging," Angew. Chem. Int. Ed. 2007, 46(36), 6816-6819 file file
  94. Min-Kyu Han, Moon-Hyeong Seo, Dohoon Lee, Seung Hyun Kim, Hae-Sim Park, and Hak-Sung Kim; "Optimization of Critical Factors Affecting the Performance of Allergen Chip for Analysis of Allergen-specific Human IgE in Serum," Anal. Sci. 2007, 23(5), 545-549 file
  95. Young-Hee Oh, Young-Pil Kim, and Hak-Sung Kim; "SUMO (Small Ubiquitin-like Modifier) Chip for Analysis of SUMO-conjugaion to a Target Protein," Biochip J. 2007, 1(1), 28-34 file
  96. Dong-Yoon Jang, Young-Pil Kim, Hak-Sung Kim, Sang-Hee Ko Park, Sung-Yool Choi and Yang-Kyu Choi; "Sub-lithographic Vertical Gold Nanogap for Label Free Electrical Detection of Protein-Ligand Binding," J. Vac. Sci. Technol. B. 2007, 25(2), 443-447 file
  97. Young Ki Hahn*, Zongwen Jin*, Joo H. Kang, Eunkeu Oh, Min-Kyu Han, Hak-Sung Kim, Jung-Tak Jang, Jae-Hyun Lee, Jinwoo Cheon, Seung Hyun Kim, Hae-Sim Park, and Je-Kyun Park (*equal contribution); "Magnetophoretic immunoassay of allergen-specific IgE in an enhanced magnetic field gradient," Anal. Chem. 2007, 79(6), 2214-2220 file
  98. Young-Pil Kim, Mi-Young Hong, Jinmo Kim, Eunkeu Oh, Hyun Kyong Shon, Dae Won Moon, Hak-Sung Kim, and Tae Geol Lee; "Quantitative Analysis of Surface-Immobilized Protein by TOF-SIMS: Effects of Protein Orientation and Trehalose Additive," Anal. Chem. 2007, 79(4), 1377-1385 file
  99. Xing-Jiu Huang, Hyung-Soon Im, Do-Hoon Lee, Hak-Sung Kim, and Yang-Kyu Choi; "Ferrocene Functionalized Single-Walled Carbon Nanotube Bundles. Hybrid Interdigitated Construction film for L-Glutamated Detection," J. Phys. Chem. C. 2007, 111(3), 1200-1206 file
  100. Young-Hee Oh*, Mi-Young Hong*, Zongwen Jin, Taeryong Lee, Min-Kyu Han, Sunyoung Park and Hak-Sung Kim (*equal contribution); "Chip-based analysis of SUMO (small ubiquitin-like modifier) conjugation to a target protein," Biosens. Bioelectron. 2007, 22, 1260-1267 file
  101. Min-Kyu Han, Mi-Young Hong, Dohoon Lee, Dong-Eun Lee, Geon Youp Noh, Jin-Ho Lee, Sung-Ho Kim and Hak-Sung Kim; "Expression Profiling of Proteins in L-Threonine Biosynthetic Pathway of Escherichia coli by using Antibody Microarray," Proteomics 2006, 6, 5929-5940 file
  102. Xing-Jiu Huang, Hyung-Soon Im, Oktay Yarimaga, Ju-Hyun Kim, Do-Hoon Lee, Hak-Sung Kim, and Yang-Kyu Choi; "Direct Electrochemistry of Uric Acid at Chemically Assembled Carboxylated Single-Walled Carbon Nanotubes Net-like Electrode," J. Phys. Chem. B. 2006, 110(43), 21850-21856 file
  103. Eunkeu Oh, Dohoon Lee, Young-Pil Kim, Seung Youp Cha, Doo-Beyong Oh, Hyun Ah Kang, Jungbae Kim, and Hak-Sung Kim; "Nanoparticle-based Energy Transfer for Rapid and Simple Detection of Protein Glycosylation," Angew. Chem. Int. Ed. 2006, 45(47), 7959-7963 file file
  104. Kwang-Seok Yun, Dohoon Lee, Hak-Sung Kim, and Euisik Yoon; "A microfluidic chip for measurement of biomolecules using a microbead-based quantum dot fluorescence assay," Measurement Science and Technology, 17(12), 3178-3183 file
  105. Xing-Jiu Huang, Yang-Kyu Choi, Hyung-Soon Im, Oktay Yarimaga, Euisik Yoon, and Hak-Sung Kim; "Aspartate Aminotransferase (AST/GOT) and Alanine Aminotransferase (ALT/GPT) Detection Techniques," Sensors, 2006, 6, 756-782 file
  106. Xing-Jiu Huang, Hyung-Soon Im, Oktay Yarimaga, Ju-Hyun Kim, Doon-Yoon Jang, Do-Hoon Lee, Hak-Sung Kim, and Yang-Kyu Choi; "Electrochemical behavior of needle-like and forest-like single walled carbon nanotube electrodes," J. Electroanal. Chem. 2006, 594(1), 27-34 file
  107. Young-Pil Kim, Mi-Young Hong, Hyun Kyung Shon, Dae Won Moon, Hak-Sung, Kim, and Tae Geol Lee; "Quantitative ToF-SIMS study of surface-immobilized streptavidin," Appl. Surf. Sci. 2006, 252, 6801-6804 file
  108. Young-Pil Kim, Eunkeu Oh, Mi-Young Hong, Dohoon Lee, Min-Kyu Han, Hyun Kyung Shon, Dae Won Moon, Hak-Sung Kim, and Tae Geol Lee; "Gold nanoparticle-enhanced secondary ion mass spectrometry imaging of peptides on self-assembled monolayers," Anal. Chem. 2006, 78(6), 1913-1920 file file
  109. Park HS, Nam SH, Lee JK, Yoon CN, Mannervik B, Benkovic SJ, and Kim HS; "Design and evolution of new catalytic activity with an existing protein scaffold," Science 2006, 311, 535-538 file file file
  110. Lee J, Lee D, Oh E, Kim J, Kim YP, Jin S, Kim HS, Hwang Y, Kwak JH, Park JG, Shin CH, Kim J, and Hyeon T; "Preparation of a magnetically switchable bio-electrocatalytic system employing cross-linked enzyme aggregates in magnetic mesocellular carbon foam," Angew. Chem. Int. Ed. 2005, 44, 7427-7432 file file
  111. Dohoon Lee, J. Lee, J. Kim, J. Kim, H. B. Na, B. Kim, C.-H. Shin, J. H. Kwak, A. Dohnalkova , J. W. Grate , T. Hyeon, and H.-S. Kim; "Simple fabrication of a highly sensitive and fast glucose biosensor using enzymes immobilized in mesocellular carbon foam," Adv. Mater. 2005, 17, 2828-2833 file
  112. Hong MY, Lee D, and Kim HS; "Kinetic and equilibrium binding analysis of protein- ligand interactions at poly(amidoamine) dendrimer monolayers," Anal. Chem. 2005, 77(22), 7326-7334 file file
  113. Nam SH, Park HS, and Kim HS; "Evolutionary relationship and application of a superfamily of cyclic amidohydrolase enzyme," Chem. Rec. 2005, 5, 298-307 file
  114. Won BY, Choi HG, Kim KH, Byun SY, Kim HS, Yoon HC; "Bioelectrocatalytic signaling from immunosensors with back-filling immobilization of glucose oxidase on biorecognition surfaces," Biotechnol Bioeng. 2005, 89(7), 815-821 file
  115. Oh E, Hong MY, Lee D, Nam SH, Yoon HC, Kim HS; "Inhibition assay of biomolecules based on fluorescence resonance energy transfer (FRET) between quantum dots and gold nanoparticles," J. Am. Chem. Soc. 2005, 127(10), 3270-3271 file file
  116. Seok HJ, Hong MY, Kim YJ, Han MK, Lee D, Lee JH, Yoo JS, Kim HS; "Mass spectrometric analysis of affinity-captured proteins on a dendrimer-based immunosensing surface: investigation of on-chip proteolytic digestion," Anal Biochem. 2005, 337(2), 294-307 file
  117. Cheon YH, Park HS, Kim JH, Kim Y, and Kim HS; "Manipulation of the active site loops of D-hydantoinase, a (beta/alpha)8-barrel protein, for modulation of the substrate specificity," Biochemistry 2004, 43(23), 7413-7420 file
  118. Hyun C. Yoon and Hak-Sung; "Bioelectrocatalyzed signal amplification for affinity interactions at chemically modified electrodes," Biotechnology and Bioprocess Engineering, 2004, 9, 107-111 file
  119. Mi-Young Hong, Young-Ja Kim, Jae-Wook Lee, Ki-Moon Kim, Jung-Hwa Lee, Jong-Shin Yoo, Sung-Hun Bae, Byong-Seok Choi, and Hak-Sung Kim; "Synthesis and Characterization of Tri(ethylene Oxide)-Attached Poly(amidoamine) Dendrimer Layers on Gold," J. Colloid Interf. Sci. 2004, 274, 41-48 file
  120. Park HS, Oh KH, and Kim HS; "Improving the functional expression of N-carbamoylase by directed evolution using the green fluorescent protein fusion reporter system," Methods Enzymol. 2004, 388, 187-95 file
  121. Sung-Hun Nam, Ki-Hoon Oh, Geun-Joong Kim, and Hak-Sung Kim; "Functional Tuning of a Salvaged Green Fluorescent Protein Variant with a New Sequence Space by Directed Evolution," Protein Eng. 2003, 16(12), 1099-1105 file
  122. Jin-Ho Lee, Dong-Eun Lee, Bheong-Uk Lee, and Hak-Sung Kim; "Global Analyses of Transcriptomes and Proteomes of a Parent Strain and an L-Threonine-Overproducing Mutant Strain," J. Bacteriol. 2003, 185(18), 5442-5451 file
  123. Jongchul Yoon, Bora Oh, Kyunggon Kim, Jung Eun Park, Jimin Wang, Hak-Sung Kim and Youngsoo Kim; "Modifying the oligomeric state of cyclic amidase and its effect on enzymatic catalysis," BBRC 2003, 310, 651-659 file
  124. Young-Hoon Cheon, Hee-Sung Park, Sang-Chul Lee, Dong-Eun Lee, and Hak-Sung Kim; "Structure-based mutational analysis of the active site residues of D-hydantoinase," J. Mol. Catal. B-Enzym. 2003, 26, 217-222 file
  125. Hak-Sung Kim; "Biocatalytic activity in Korea (Editorial)," J. Mol. Catal. B-Enzym. 2003, 26, 113-114 file
  126. Mi-Young Hong, Dohoon Lee, Hyun C. Yoon, and Hak-Sung Kim; "Patterning biological Molecules onto Poly(amidoamine) Dendrimer on Gold and Glass," Bull. Korean Chem. Soc. 2003, 24(8), 1197-1202 file
  127. Mi-Young Hong, Hyun C. Yoon, and Hak-Sung Kim; "Protein-Ligand Interactions at Poly(amidoamine) Dendrimer Monolayers on Gold," Langmuir 2003, 19(2), 416-421 file
  128. Cheon YH, Kim HS, Han KH, Abendroth J, Niefind K, Schomburg D, Wang J, Kim Y; "Crystal structure of D-hydantoinase from Bacillus stearothermophilus: insight into the stereochemistry of enantioselectivity," Biochemistry. 2002 Jul 30; 41(30):9410-7 file
  129. KH Oh, SH Nam, and HS Kim; "Directed evolution of N-carbamyl-D-amino acid amidohydrolase for simultaneous improvement of oxidative and thermostability," Biotechnology Progress, 2002 May-Jun; 18(3):413-7 file
  130. Park JH, Oh KH, Lee DC, Kim HS; "Modeling and kinetic analysis of the reaction system using whole cells with separately and co-expressed D-hydantoinase and N-carbamoylase," Biotechnol Bioeng. 2002 Jun 30; 78(7):779-93 file
  131. KH Oh, SH Nam, and HS Kim; "Improvement of oxidative and thermostability of N-carbamyl-D-amino acid amidohydrolase by directed evolution," Protein Engineering, 2002 15: 689-695 file
  132. Kim, Geun-Joong and Hak-Sung Kim; "A Microbial D-Hydantoinase is Stabilized and Overexpressed as a Catalytically Active Dimer by Truncation and Insertion of the C-Terminal Region," J. Microbiol. Biotechnol. 2002 12(2), 242-248 file
  133. C Yoon, DH Lee, and HS Kim; "Reversible affinity interactions of antibody molecules at functionalized dendrimer monolayer: affinity-sensing surface with reusability," Analytica Chimica Acta, 456, 209-218, 2002 file
  134. MY Hong, JY Chang, HC Yoon, and HS Kim; "Development of a screen-printed amperometric biosensor for determination of L-Lactate dehydrogenase level," Biosensors and Bioelectronics , 17, 13-18, 2002 file
  135. HC Yoon, HS Kim; "BT-IT fusion technology," Prospectives of Industrial Chemistry. 13 Volume 5, No 4, 5-12. 2002
  136. Geun-joong Kim, Dong-Eun Lee, and Hak-Sung Kim; "Characterization and Evaluation of a Distinct Fusion Ability in the Functionally Related Cyclic Amidohydrolase Family Enzymes," Biotechnol. Bioprocess Eng. 13 7:155-162, 2002 file
  137. HC Yoon, MY Hong, and HS Kim; "Reversible association/dissociation reaction of avidin on the dendrimer monolayer functionalized with a biotin-analog for a reagentless affinity-sensing surface," Langmuir,17, 1234-1239, 2001 file
  138. GJ Kim, YH Cheon, MS Park, HS Park and HS Kim; "Generation of protein lineages with new sequence spaces by functional salvage screen," Protein Engineering ,14(9), 647-654, 2001 file
  139. HS Park and HS Kim; "Genetic and structural organization of the aminophenol catabolic operon and its implication for evolutionary process," Journal of Bacteriology, 183(17), 5074-5081, 2001 file
  140. GJ Kim, DE LEE, and HS Kim; "High-level expression and one-step purificatio of cyclic amidohydrolase family enzyme," Protein Expression and Purification, ,23, 128-133, 2001 file
  141. KH Oh, GJ Kim, JH Park, and HS Kim; "Structural and functional importance of two glutamate residues, Glu47 and Glu146, conserved in N-carbamyl D-amino acid amidohydrolases," Journal of Microbiology and Biotechnology,11(1), 29-34, 2001 file
  142. GJ Kim, DE Lee, and HS Kim; "Functional Expression and Characterization of the Two Cyclic Amidohydrolase Enzymes, Allantoinase and a Novel Phenylhydantoinase, from Escherichia coli," Journal of Bacteriology,182, 7021-7028, 2000 file
  143. YH Cheon, GJ Kim, and HS Kim; "Stabilization of D-hydantoinase by intersubunit cross-linking," Journal of Molecular Catalysis B: Enzymatic 11, 29-35, 2000 file
  144. HC Yoon, MY Hong, and HS Kim; "Functionalization of a Poly(amidoamine) dendrimer with ferrocenyls and its application to the construction of a reagentless enzyme electrode," Analytical Chemistry, 72, 4420-4427, 2000 file
  145. JH Park, GJ Kim, and HS Kim; "Production of D-amino acid using whole cells of recombinant Escherichia coli with separately and coexpressed D-hydantoinase and N-carbamoylase," Biotechnology Progress, 16(4 564-570, 2000 file
  146. HC Yoon, MY Hong, and HS Kim; "Affinity biosensor for avidin using a double-functionalized dendrimer monolayer on gold electrode," Analytical Biochemistry, 282 (1), 121-128, 2000 file
  147. HC Yoon, HS Kim; "Multilayered Assembly of Dendrimers with Enzymes on Gold: Thickness Controlled Biosensing Interface," Analytical Chemistry, 72, 922 - 926, 2000 file
  148. HS Park and HS Kim; "Identification and characterization of NB catabolic plasmids of Pseudomonas putida HS12," Journal of Bacteriology, 182 (3), 573 - 580, 2000 file
  149. GJ Kim, YH Cheon and HS Kim; "Direct evolution of a novel N-carbamylase/D-hydantoinase fusion enzyme for functional expression with enhanced stability," Biotechnology and Bioengineering, 68 (2), 211-217, 2000 file
  150. GJ Kim, DE Lee and HS Kim; "Construction and evaluation of a novel bifunctional N-carbamylase/D-hydantoinase fusion enzyme," Applied and Environmental Microbiology, 66 (5), 2133-2138, 2000 file
  151. JY Lee, HS Park and HS Kim; "Adenosylcobalamin-Mediated Methyl Transfer by Toluate cis-Dihydrodiol Dehydrogenase of the TOL Plasmid pWW0," Journal of Bacteriology, 181 (9), 2953 - 2957, 1999 file
  152. HS Park, SJ Lim, YK Chang, AG Livingston and HS Kim; "Degradation of Chloronitrobenzenes by a Coculture of Pseudomonas putida and a Rhodococcus sp," Applied and Environmental Microbiology, 65 (3), 1083 - 1091, 1999 file
  153. JH Park, GJ Kim, SG Lee and HS Kim; "Purification and characterization of thermostable D-hydantoinase from Bacillus thermocatenulatus GH2," Applied Biochemistry and Biotechnology, 81 (1), 53 - 65, 1999 file
  154. DC Lee, JH Park, GJ Kim, HS Kim; "Modeling, Simulation, and Kinetics Analysis of a Heterogeneous Reaction System for the Enzymatic Conversion of Poorly Soluble Substrate," Biotechnology and Bioengineering, 64, 272 - 283, 1998 file
  155. DC Lee, JH Park, GJ Kim and HS Kim; "Modeling, simulation, and kinetic analysis of a heterogeneous reaction system for the production of D-amino acids using thermostable D-hdyantoinase," Biotechnol. Bioeng., 64 (3), 272-283, 1998 file
  156. DC Lee, GJ Kim and HS Kim; "A cultivation strategy of recombinant E. coli for mass production of thermostable D-hydantoinase," Anal NY Acad. Sci, 864, 371-374, 1998 file
  157. GJ Kim, JH Park, DC Lee and HS Kim; "Engineering the thermostable D-hdyantoinases from two thermophilic Bacilli based on their primary structure," Anal NY Acad. Sci., 864, 332-336, 1998 file
  158. JH Park, GJ Kim and HS Kim; "Biochemical properties of thermostable D-hydantoinase from Bacillus thermocatenulatus GH2," Anal NY Acad. Sci., 864, 337-340, 1998 file
  159. DC Lee and HS Kim; "Optimization of a heterogeneous reaction system for thee production of optically active D-amino acids using thermostable D-hydantoinase," Biotechnol. Bioeng., 60 (6), 729-738, 1998 file
  160. GJ Kim and HS Kim; "C-Terminal Regions of D-Hydantoinase are Non-Essential for Catalysis, but Affect the Oligomeric Structure," Biochem. Biophys. Res. Commun., 243 (1), 96-100, 1998 file
  161. GJ Kim and HS Kim; "Identification of the structural similarity in the fuctionally relatedamidohydrolases acting on the cyclic amide ring," Biochem J., 330, 295-302, 1998 file
  162. SH Kim, HC Yoon and HS Kim; "Development of quartz crystal microbalance-based immunosensor for the determination of low-density lipoprotein," Kor. J. Biotechnol. Bioeng., 13 (4), 337-342, 1998
  163. DC Lee, GJ Kim, YK Cha, CY Lee and HS Kim; "Mass Production of Thermostable D-Hydantoinase by Batch Culture of Recombinant Escherichia Coli with a Constitutive Expression System," Biotechnol. Bioeng., 56 (4), 449-55, 1997 file
  164. HS Park, JY Lee, and HS Kim; "Production of L-DAPA(3,4-Dihydroxyphenyl-L-alanine) fromBenzene by Using A Hybrid Pathway," Biotechnol. Bioeng., 58, 339-343, 1997 file
  165. GJ Kim, JH Park, DC Lee, HS Roh and HS Kim; "Primary Structure, sequenceanalysis, and expression of the thermostable D-hydantoinase from Bacillus stearothermophilus SD1," Mol. Gen. Genet., 255, 152-156, 1997 file
  166. GJ Kim, SG Lee, JH Park and HS Kim; "Direct detection of the hydantoinase activityon solid agar plates and electrophoretic acrylamide gels," Biotechnol.Tech., 11 (7), 511-513, 1997 file file
  167. SG Lee, DC Lee and HS Kim; "Purification and Characterization of ThermostableD-Hydantoinase from Thermophilic Bacillus stearothermophilus SD-1," Appl.Biochem.Biotechnol., 62, 251-266, 1997 file
  168. DC Lee and HS Kim; "Use of Methicillin and Ampicillin Mixture as a Selective Pressure in theCultivation of Recombinant E. coli," Biotchnol. Tech., 10 (12), 937-940, 1996 file
  169. HS Ro, SP Hong, HJ Seo, T Yoshimura, N Esaki, K Soda, HS Kim,MH Sung; "Site-directedmutagenesis of the amino acid residues in B-strand III of D-amino acid aminotransferase ofbacillus sp. YM-1," FEBS Letters, 398, 141-145, 1996 file
  170. DC Lee, SG Lee, SP Hong, MH Sung and HS Kim; "Cloning andOverexpression of Thermostable D-Hydantoinase from Thermophile in E. coli and Its Application to the Synthesis of OpticallyActive D-Amino Acids," Annal. N.Y. Acad. SCi., 799, 401-405, 1996 file
  171. DC Lee, SG Lee and HS Kim; "Production of D-p-hydroxyphenylglycine from D,L-5-(4-hydroxyphenyl)hydantoin using immobilized thermostable D-hydantoinase from Bacillus stearothermophilis SD-1," Enzyme-Microb Technol., 18, 35-40, 1996 file
  172. HC Yoon and HS Kim; "Electrochemical caracteristics of a carbon-based thick-film L-lactate biosensorusing L-lactate dehydrogenase," Analytica Chimica Acta, 336, 57- 65, 1996 file
  173. MC Shin, HC Yoon and HS Kim; "Experimental and Theoretical Analyses on Factors Affecting thePerformance of Polypyrrole/Glucose Oxidase Biosensor: Permeability Aspect of Polypyrrole Film," Analytical Sciences,12, 597-604, 1996 file
  174. MC Shin, HC Yoon and HS Kim; "In situ biochemical reduction of interference in an amperometricbiosensor with a novel heterobilayer configuration of polypyrrole/glucose oxidase/horseradish peroxidase," Analytica ChimicaActa, 329. 223-230, 1996 file
  175. JH Cho, MC Shin and HS Kim; "Electrochemical adsorption of glucose oxidase onto polypyrrolefilm for the construction of a glucose biosensor," Sensors and Actuators B, 30, 137-141, 1996 file
  176. MC Shin and HS Kim; "Electrochemical characterization of polypyrrole/glucose oxidase biosensor: PartII. Optimal preparation conditions for the biosensor," Biosensors-Bioelectron., 11 (1), 171-178, 1996 file
  177. MC Shin and HS Kim; "Electrochemical characterization of polypyrrole/glucose oxidase biosensor: Part I.Influence of enzyme concentration on the growth and properties of the film," Biosensors-Bioelectron., 11 (1), 161-169, 1996 file
  178. MC Shin and HS Kim; "Effects of Enzymatic Concentration and Film Thickness on the AnalyticalPerformance of a Polypyrrole/Glucose Oxidase Biosensor," Analytical Letters, 28 (6), 1017-1031, 1995 file
  179. HC Yoon and HS Kim; "Electrocatalytic properties of metal-dispersed carbon paste electrode for reagentless L-lactate biosenso," Korean J. Biotechnol. Bioeng, 11 (4), 489-496, 1996 file
  180. HS Kim; "Metabolic engineering in bioremedication," The Microorganisms and Industry, 22, 276-280, 1996
  181. JK Park, MC Shin, SG Lee and HS Kim; "Flow Injection Analysis of Glucose, Fructose,and Sucrose Using a Biosensor Constructed with Permeabilized Zymomonas mobilis and Invertase," Biotechnol. Prog., 11, 58-63, 1995 file
  182. GJ Kim and HS Kim; "Optimization of the Enzymatic Synthesis of D-p-Hydroxyphenylglycine fromDL-5-substituted Hydantoin using D-Hydantoinase and N-Carbamoylase," Enzyme-Microb.Technol., 17, 63-67,1995 file
  183. SG Lee, DC Lee, SP Hong, MH Sung and HS Kim; "Thermostable D-Hydantoinase fromThermophilic Bacillus stearothermophilus SD-1: Characteristics of Purified Enzyme," Appl. Microbiol.Biotechnol. 43, 270-276, 1995 file
  184. GJ Kim and HS Kim; "Optimal Reaction Conditions for the Enzymatic Synthesis of Optically ActiveD-p-Hydroxyphenylglycine from 5-substituted Hydantoin Using D-Hydantoinase and N-Carbamoylase," Annal.N.Y.Acad.Sci., 750, 185-189, 1995 file
  185. KH Jung, JY Lee and HS Kim; "Biodegradation of Nitrobenzene Through a Hybrid Pathway inPseudomonas putida," Biotechnol. Bioeng., 48, 625-630, 1995 file
  186. JY Lee, KH Jung, SH Choi and HS Kim; "Combination of the tod anf tol Pathways inRedesigning a Metabolic Route of Pseudomonas putida for the Mineralization of a Benzene, Toluene, and p-Xylene Mixture," Appl.Environ.Microbiol., 61 (6), 2211- 2217, 1995 file
  187. JY Lee, KH Jung and HS Kim; "Amplification of Toluene Dioxygenase Genes in a HybridPseudomonas Strain to Enhance the Biodegradation of Benzene, Toluene and p-Xylene Mixture," Biotechnol. Bioeng., 45, 488-494, 1995 file
  188. JY Lee and HS Kim; "Environmental Biotechnology for the Degradation of Recalcitrant Aromatic-Hydrocarbons," Life Chemistry Reports, 12, 105-135, 1994 file
  189. YB Choi, JY Lee and HS Kim; "Biodegradation of Toluene using Biofilms in a Bubble Column Bioreactor," J. Microbiol. Biotechnol., 5 (1), 41-47, 1995 file
  190. JY Lee, JR Roh and HS Kim; "Metabolic Engineering of Pseudomonas putida for theSimultaneous Biodegradation of Benzene, Toluene, and p-Xylene Mixture," Biotechnol. Bioeng., 43, 1146-1152, 1994 file
  191. SG Lee, DC Lee, MH Sung and HS Kim; "Isolation of ThermostableD-Hydantoinase-Producing Thermophilic Bacillus sp SD-1," Biotechnol. Lett., 16 (5), 461-466, 1994 file
  192. GJ Kim and HS Kim; "Adsorptive Removal of Inhibitory By-Product in the Enzymatic Production of Optically Active D-p-Hydroxyphenylglycine from 5-Substituted Hydantoin," Biotechnol.Lett., 16 (1), 17-22, 1994 file
  193. DM Kim, GJ Kim and HS Kim; "Enhancement of Operational Stability of Immobilized WholeCell D-Hydantoinase," Biotechnol. Lett., 16 (1), 11-16, 1994 file
  194. SG Lee and HS Kim; "Optimal Operating Policy of the Ultrafiltration Membrane Bioreactor forEnzymatic Hydrlysis of Cellulose," Biotechnol. Bioeng., 42. 737-746, 1993 file
  195. HK Lim, JY Lee and HS Kim; "Cometabolism in the Biodegradation of Benzene, Toluene, andp-Xylene Mixture by Isolated Pseudomonas fluorescence BE103," J. Microbiol. Biotechnol., 4, 163-67, 1994 file
  196. DM Kim and HS Kim; "Enzymatic synthesis of D-p-hydroxyphenylglycine fromDL-p-hydroxyphenylhydantoin in the presence of organic cosolvent," Enzyme Microb.Technol., 15. 530-534, 1993 file
  197. TJ Kim, YD Lee and HS Kim; "Enzymatic Production of Cyclodextrins from Milled Corn Starchin an Ultrafiltration Membrane Bioreactor," Biotechnol. Bioeng., 41. 88-94, 1993 file
  198. JY Lee, YB Choi and HS Kim; "Simultaneous Biodegradation of Toluene and p-Xylene in a Novel Bioreactor: Experimental Results and Mathematical Analysis," Biotechnol.Prog., 9 (1), 46-53, 1993 file
  199. TJ Kim, YD Lee and HS Kim; "Production of Cyclodextrins from Unliquefied Cornstarch Using Cyclodextrin Glycosyltransferase in a Membrane Bioreactor," Annal. N.Y. Acad. Sci., 672, 552-557, 1992 file
  200. MCl Shin, JK Park and HS Kim; "Development flow injection analysis system for amperometric determination of cholesterol using immohilized enzyme clumns," Korean J. Biotechnol. Bioeng., 8 (4), 328-335, 1993 file
  201. YB Choi, JY Lee, HK Lim and HS Kim; "A Novel Method to Supply the InhibitoryAromatic Compounds in Aerobic Biodegradation Process," Biotechnol.Tech., 6 (6) 489-492, 1992 file
  202. YB Choi, JY Lee and HS Kim; "A Novel Bioreactor for the Biodegradation of InhibitoryAromatic Solvents : Experimental Results and Mathematical Analysis," Biotechnol.Bioeng., 40, 1403-1411,1992 file
  203. YD Lee and HS Kim; "Enhancement of enzymatic production of cyclodextrins by organic solvents," Enzyme Microb. Technol., 13 (6), 499-503, 1992 file
  204. YD Lee and HS Kim; "Effect of Organic Solvents on Enzymatic Production of Cyclodextrins fromUnliquefied Corn Starch in an Attrition Bioreactor," Biotechnol. Bioeng., 39. 977-983, 1992 file
  205. DM Kim and HS Kim; "Continous Production of Gluconic Acid and Sorbitol from Jerusalem Artichoke and Glucose Using an Oxidoreductase of Zymomonas mobilis and Inulinase," Biotechnol. Bioeng., 39, 336-342, 1992 file
  206. HS Ro and HS Kim; "Continous Production of Gluconic Acid and Sorbitol from sucrose Using Invertase and an Oxidoreductase of Zymomonas mobilis," Enzyme Microb. Technol., 13, 920-924, 1991 file
  207. JK Park, HS Ro and HS Kim; "A new biosensor for specific determination of Sucrose using an Oxidoreductase of Zymomonas mobilis and Invertase," Biotechnol. Bioeng., 38, 217-223, 1991 file
  208. JK Park and HS Kim; "A new biosensor for specific determination of glucose or fructose using an oxidoreductase of Zymomonas mobilis," Biotechnol. Bioeng., 36, 744-749, 1990 file
  209. WJ Kim, JK Park and HS Kim; "Continuous production of gluconic acid and sorbitol from glucose and fructose using permeabilized cells of Zymomonas mobilis," Kor. J. Appl. Microbiol. Bioeng., 19 (1), 70 - 75, 1991
  210. CK Choi, YH Park and HS Kim; "A rapid analysis of cholesterol and its fermentative products by HPLC," J. chromatogr., 398, 372-374, 1987 file
  211. YB Choi, SK Choi, YH Park and HS Kim; "Biotransformation of Progesterone to 11-alpha-hydroxyprogesterone by Using Rhizopus nigricans at Elevated Concentration of the Substrate," Kor. J. Appl. Microbial. Bioeng., 18 (1), 66-70, 1990
  212. YB Choi, SK Choi, YH Park and HS Kim; "Enhancement of Biotransformation Yield in 11-alpha-hydroxylation of Progesterone by Continuous Addition of the Substrate," Kor. J. Appl. Microbiol. Bioeng., 18 (3), 280 - 285, 1990
  213. HS Kim, P Minard, MD Legoy and D Thomas; "Inactivation of 3??-hydroxysteroid dehydrogenase by superoxide radicals," Biochem. J., 233 (3), 493-97, 1986 file
  214. MD Legoy, HS Kim and D Thomas; "Use of alcohol dehydrogenase for flavor production," Eur.Congr.Biotechnol., 2, 497-501, 1984 file
  215. DDY Ryu, HS Kim and H Taguchi; "Intrinsic kinetic parameters of immobilized Yeast Cells," J. Ferment. Technol., 62 (3), 255-61, 1984 file
  216. C Kim, HS Kim and DDY Ryu; "Optimization of operating temperature for continuous glucose isomerase reactor system," Biotechnol. Bioeng., 24 (8), 1889-96, 1982 file
  217. HS Kim and DDY Ryu; "Continuous glutamate production using an immobilized whole-cell system," Biotechnol. Bioeng., 24 (10), 2167-74, 1982 file

django-powered, by Hyun-Ho Kyeong

Logo-designed, by Hong-Sik Kim