Papers

Type Papers Patents Conferences
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  1. Joong-jae Lee*, Hyun Jung Kim*, Chul-Su Yang*, Hyun-Ho Kyeong, Jung-Min Choi, Da-Eun Hwang, Jae-Min Yuk, Keunwan Park, Yu Jung Kim, Seung-Goo Lee, Dongsup Kim, Eun-Kyeong Jo, Hae-Kap Cheong, Hak-Sung Kim (*equal contribution); "A high-affinity protein binder that blocks the IL-6/STAT3 signaling pathway effectively suppresses non-small cell lung cancer," Molecular Therapy, 2014, 22(7), 1254-1265 file file
  2. Moon-Hyeong Seo, Jeongbin Park, Eunkyung Kim, Sungchul Hohng, Hak-Sung Kim; "Protein conformational dynamics dictate the binding affinity for a ligand," Nature Communications, 2014, 5, 3724 file
  3. Mi-Suk Kang*, Sang-Soo Han*, Mi-Young Kim, Bu-Youn Kim, Jong-Pil Huh, Hak-Sung Kim, Jin-Ho Lee (*equal contribution); "High-level expression in Corynebacterium glutamicum of nitrile hydratase from Rhodococcus rhodochrous for acrylamide production," Applied Microbiology and Biotechnology, 2014, 98(10), 4379-4387 file
  4. Su-Lim Choi, Eugene Rha, Sang Jun Lee, Haseong Kim, Kilkoang Kwon, Young-Su Jeong, Young Ha Rhee, Jae Jun Song, Hak-Sung Kim, and Seung-Goo Lee; "Toward a Generalized and High-throughput Enzyme Screening System Based on Artificial Genetic Circuits," ACS Synthetic Biology, 2014, 3(3), 163-171 file
  5. Jung Min Choi, Moon-Hyeong Seo, Hyun-Ho Kyeong, Eunkyung Kim, and Hak-Sung Kim; "Molecular basis for the role of glucokinase regulatory protein as the allosteric switch for glucokinase," PNAS, 2013, 110(25), 10171-10176 file
  6. So-Young Lee, Young Don Hong, Hak-Sung Kim, Sun-Ju Choi; "Synthesis and application of a novel cysteine-based DTPA-NCS for targeted radioimmunotherapy," Nuclear Medicine and Biology, 2013, 40, 424-429 file
  7. Seong-Min Jo*, Youngwook Kim*, Young-Su Jeong, Young Hee Oh, Keunchil Park, Hak-Sung Kim (*equal contribution); "Rapid detection of exon2-deleted AIMP2 mutation as a potential biomarker for lung cancer by molecular beacons," Biosensors and Bioelectronics, 2013, 46, 142-149 file
  8. Eunkyung Kim*, Sanghwa Lee*, Aram Jeon, Jung Min Choi, Hee-Seung Lee, Sungchul Hohng, Hak-Sung Kim (*equal contribution); "A single-molecule dissection of ligand binding to a protein with intrinsic dynamics," Nature Chemical Biology, 2013, 9, 313-318 file
  9. Jihyo Kim*, Moon-Hyeong Seo*, Sangsik Lee, Kyukwang Cho, Aerin Yang, Kyunghwa Woo, Hak-Sung Kim, and Hee-Sung Park (*equal contribution); "Simple and Efficient Strategy for Site-Specific Dual Labeling of Proteins for Single-Molecule Fluorescence Resonance Energy Transfer Analysis," Anal. Chem. 2013, 85(3), 1468-1474 file
  10. Jang-Hyuk Ahn, Young-Su Jeong, Tae Geol Lee, Young-Pil Kim, and Hak-Sung Kim; "Sensitive and multiplexed analysis of aflatoxins using time-of-flight secondary ion mass spectrometry," BioChip Journal, 2012, 6(1), 34-40 file
  11. Jang-Hyuk Ahn, Young-Pil Kim, and Hak-Sung Kim; "Effect of natural antioxidants on the lipid oxidation of microencapsulated seed oil," Food Control, 2012, 23(2), 528-534 file
  12. Young-Su Jeong, Su-Lim Choi, Hyun-Ho Kyeong, Jin-Hyun Kim, Eui-Joong Kim, Jae-Gu Pan, Eugene Rha, Jae Jun Song, Seung-Goo Lee and Hak-Sung Kim; "High-throughput screening system based on phenolics-responsive transcription activator for directed evolution of organophosphate-degrading enzymes," Protein Engineering Design & Selection, 2012, 25(11), 725-731 file
  13. Young-Pil Kim, Sang Jin Park, Dohoon Lee, and Hak-Sung Kim; "Electrochemical glucose biosensor by electrostatic binding of PQQ-glucose dehydrogenase onto self-assembled monolayers on gold," Journal of Applied Electrochemistry, 2012, 42(6), 383-390 file
  14. Bum Jin Oh, Moon-Hyeong Seo, and Hak-Sung Kim; "Insignificant role of the N-terminal cobalt-binding site of albumin in the assessment of acute coronary syndrome:discrepancy between the albumin cobalt-binding assay and N-terminal-targeted immunoassay," Biomarkers, 2012; 17(5): 394-401 file
  15. Sang-Chul Lee*, Keunwan Park*, Jieun Han*, Joong-jae Lee*, Hyun Jung Kim, Seungpyo Hong, Woosung Heu, Yu Jung Kim, Jae-Seok Ha, Seung-Goo Lee, Hae-Kap Cheong, Young Ho Jeon, Dong-sup Kim, and Hak-Sung Kim (*equal contribution); "Design of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineering," PNAS, 2012, 109(9), 3299-3304 file
  16. Jieun Han*, Hyun Jung Kim*, Sang-Chul Lee, Seungpyo Hong, Keunwan Park, Young Ho Jeon, Dong-sup Kim, Hae-Kap Cheong, and Hak-Sung Kim (*equal contribution); "Structure-based rational design of a Toll-like receptor 4 (TLR4) decoy receptor with high binding affinity for a target protein," PLoS ONE, 2012, 7(2), e30929 file
  17. Yiseul Ryu, Zongwen Jin, Mun Suk Kang, and Hak-Sung Kim; "Increase in the detection sensitivity of a lateral flow assay for a cardiac marker by oriented immobilization of antibody," BioChip J. 2011, 5(3), 193-198 file
  18. Moon-Hyeong Seo*, Tae-Sun Lee*, Eunkyung Kim*, Young Lag Cho, Hee-Sung Park, Tae-Young Yoon, and Hak-Sung Kim (*equal contribution); "Efficient Single-Molecule Fluorescence Resonance Energy Transfer Analysis by Site-Specific Dual-Labeling of Protein Using an Unnatural Amino Acid," Anal. Chem. 2011, 83(23), 8849-8854 file
  19. Sunyoung Park*, Jieun Han*, Wanjung Kim, Gyun Min Lee, and Hak-Sung Kim (*equal contribution); "Rapid selection of single cells with high antibody production rates by microwell array," Journal of Biotechnology 156 (2011) 197-202 file
  20. Jang-Hyuk Ahn, Young-Pil Kim, and Hak-Sung Kim; "Effect of natural antioxidants on the lipid oxidation of microencapsulated seed oil," Food Control 23 (2012) 528-534 file
  21. Moon-Hyeong Seo, Jieun Han, Zongwen Jin, Dong-Won Lee, Hee-Sung Park, and Hak-Sung Kim; "Controlled and oriented immobilization of protein by site-specific incorporation of unnatural amino acid," Anal. Chem. 2011, 83(8), 2841-2845 file
  22. Yunxian Piao, Zongwen Jin, Dohoon Lee, Hye-Jin Lee, Hyon-Bin Na, Taeghwan Hyeon, Min-Kyu Oh, Jungbae Kim, and Hak-Sung Kim; "Sensitive and High-Fidelity Electrochemical Immunoassay using Carbon Nanotubes Coated with Enzymes and Magnetic Nanoparticles," Biosens. Bioelectron. 2011, 26, 3192-3199 file
  23. Sang-Chul Lee, Jin-Hyun Kim and Hak-Sung Kim; "Design and evolution of biocatalysts," Current Organic Chemistry, 2010, Vol14, 1894-1901 file
  24. Sunyoung Park, Wanjung Kim, Yongtae Kim, Young Dok Son, Sang-Chul Lee, Eunkyung Kim, Sung Ho Kim, Jung Hoe Kim and Hak-Sung Kim; "Array-Based Analysis of Secreted Glycoproteins for Rapid Selection of a Single Cell Producing a Glycoprotein with Desired Glycosylation," Anal. Chem. 2010, 82(13), 5830-5837 file
  25. Jin-Hyun Kim, Sang-Chul Lee, Hyun-Ho Kyeong, and Hak-Sung Kim; "A Genetic Circuit System Based on Quorum Sensing Signaling for Directed Evolution of Quorum-Quenching Enzymes," ChemBioChem, 2010, 11, 1748-1753 file file
  26. Young-Hee Oh*, Youngwook Kim*, Young-Pil Kim, Soo-Won Seo, Tetsuya Mitsudomi, Myung-Ju Ahn, Keunchil Park, and Hak-Sung Kim (*equal contribution); "Rapid detection of the epidermal growth factor receptor mutation in non-small cell lung cancer for analysis of acquired resistance using molecular beacon," The Journal of Molecular Diagnostics 2010, 12(5), 644-652 file
  27. Min-Kyu Han*, Young-Hee Oh*, Jimin Kang, Young-Pil Kim, Soowon Seo, Jhingook Kim, KeunChil Park and Hak-Sung Kim (*equal contribution); "Protein profiling in human sera for identification of potential lung cancer biomarkers using antibody microarray," Proteomics 2009, 9(24), 5544-5552 file
  28. Sung Ho Yang, Kyung-Bok Lee, Bokyung Kong, Jin-Hyun Kim, Hak-Sung Kim, Insung S. Choi; "Biomimetic Encapsulation of Individual Cells with Silica," Angew. Chem. Int. Ed. 2009, 48, 9160-9163 file
  29. Kwang-Seok Yun, Dohoon Lee, Hak-Sung Kim, Euisik Yoon; "Multifunctional microwell plate for on-chip cell and microbead-based assays," Sensors and Actuators B: Chemical, 2009. 143(1), 387-394 file
  30. Yunxian Piao, Dohoon Lee, Jinwoo Lee, Taeghwan Hyeon, Jungbae Kim, Hak-Sung Kim; "Multiplexed immunoassay using the stabilized enzymes in mesoporous silica," Biosens. Bioelectron. 2009. 25(4), 906-912 file

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